Group 701

Inflammation and Vascular Damage in Chronic Kidney Disease, Dialysis, and Kidney Transplantation. Renal Pathophysiology

Director
Maria de Los Angeles Goicoechea Diezhandino, Alberto Lazaro Fernandez
Group type
CONSOLIDATED
Research lines

Axis 1: Research in Acute Renal Failure

L1: Searching for new therapeutic alternatives in acute renal failure of different aetiology (nephrotoxic, sepsis, rhabdomyolysis...).

L2: Inhibition of cholesterol rafts as a therapeutic target in ARF

L3: Nephroprotective role of cilastatin in patients subjected to HIPEC-cisplatin.

L4: Effect of renal inflammasome on distant organ damage

L5: Inhibition of cholesterol rafts as a therapeutic target in lung and intestinal damage

L6: Malaria and acute renal failure

L7: Cardiorenal syndrome, cardiovascular damage in renal failure

Axis 2: CKD progression

L1: Role of colchicine in CKD progression

L2: RAAS blockers in elderly CKD patients without albuminuria

L3: CKD aetiology and progression

L4: Chronic kidney disease prevention and risk stratification

Axis 3: Haemodialysis and complications

L1: Clearance of protein-bound uremic toxins of medium molecular weight: HFR

L2: Potassium levels, dialysate and cardiac arrhythmias

L3: Evaluation of convective transport and online HF techniques on efficacy, tolerability and long-term prognosis of ESRD patients.

Axis 4: Vascular access

L1: Impact of isometric physical exercise in radiocephalic AVFs

Axis 5: Peritoneal dialysis and home haemodialysis

L1: Implementation of new modalities of home dialysis

L2: Efficacy of peritoneal dialysis in refractory heart failure patients

Axis 6: Covid-19

L1: Short- and long-term efficacy of vaccination against SARS-COV2 in patients with CKD, dialysis and renal transplantation: SENCOVAC study.

Axis 7: Acute renal failure

L1: Acute renal failure code in hospitalisation

L2: Protective role of rasburicase in acute renal failure after heart surgery

L3: Acute renal failure in hypertensive disorders of pregnancy

L4: Mortality and prognosis of patients presenting with acute renal failure in hospitalisation

Axis 8: Glomerular Pathology

L1: FSGMAC-02: Identification of mutations in the MAFB gene in patients with podocytophaties. Analysis of the effect of these mutations in functional and transcriptional polarization human macrophages.

L2: TUBULO01 - Markers of tubular damage in protein nephropathies, historical correlation and progression of chronic renal disease.

Axis 9: ERC Genetics

L1: GENSEN study: Identification of genetic mutations in patients with CKD of non-inherited aetiology